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pentobarbital will reduce the extent or result of fosamprenavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.pentobarbital will lessen the level or result of suvorexant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Powerful CYP3A4 inducers may lessen suvorexant efficacy; if improve